Role of nuclear medicine assessing patients with suspected coronary artery disease

Nuclear medicine and coronary artery disease

Roberto F.E. Pedretti
School of Medicine and Surgery, University of Milano-Bicocca, Milan; Italy and Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Luca Genovese
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Luca Alberti
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Alessandro Cecilia
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Martina Cellamare
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Matteo Crippa
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Gianmarco Dacquino
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Aurora Danza
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Matteo Della Torre
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Federico Ferrari Bravo
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Giuseppe Galati
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Francesco Torlone
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy
Simona Sarzi Braga
Cardiovascular Department, IRCCS MultiMedica, Sesto S. Giovanni, Milan, Italy

Abstract

Nuclear medicine is a critical component in the field of cardiology as it provides diagnostic and prognostic insights that are essential for the effective management of heart disease.
Both single photon emission computed tomography (SPECT) and positron emission tomography (PET) play a significant role in assessing the likelihood of ischemic heart disease based on pre-test probabilities. Both SPECT and PET should be integrated into the clinical pathway according to the patient’s individual risk profile, symptoms, and initial test results. The guidelines recommend using these imaging modalities to refine risk stratification, particularly in intermediate-risk patients, and to guide further invasive diagnostic or therapeutic procedures based on the imaging findings.

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